A New Variant of Concern: The COVID-19 Omicron Variant

The world's immediate and frantic reaction to the Omicron variant's arrival could be an indication of the type of threat this new COVID-19 variant poses. Initial evidence from the South African National Institute for Communicable Diseases shows that the concern about Omicron, or B.1.1.529, is well-founded; Omicron appears to be far more transmissible than Delta.

The Omicron form has already spread over the world from its origins in Gauteng Province, South Africa, and is said to be growing exponentially in areas where it has taken hold.

Following the announcement by the scientific community of the advent of the COVID-19 Omicron strain, a discussion erupted over the effectiveness of travel prohibitions and international communication. Notably, vaccines, masks, and appropriate social distance are still the most effective weapons in defense of your and your family's safety and health, just as they were with previous variations.

This article will discuss what is known about the Omicron Variant thus far and what people can do to stay safe in the face of yet another looming COVID-19 wave.

The Omicron Variant: What the World Knows So Far

Following its recent emergence in South Africa, the World Health Organization (WHO) identified Omicron as the latest COVID-19 "variant of concern" on November 26.

According to the US Centers for Disease Control and Prevention, there is evidence that this strain of SARS-CoV-2 could increase disease transmissibility, lead to more severe cases, diminish the effectiveness of antibodies, medications, or vaccinations, or cause diagnostic detection failures.

What Is the Omicron Variant?

Omicron is a distinct strain of the coronavirus that produces COVID-19: SARS-CoV-2, like the Delta variant. However, Omicron is quite notable as other variants do not fit the requirements to get classified as variants of concern, typical of how viruses act and evolve in the real world.

Omicron is officially known as variant B.1.1.529, and according to WHO, it has a high number of mutations. Some of these mutations are worrying experts. Moreover, according to preliminary studies, this strain may increase the chance of re-infection.

Vaccines vs. Omicron: Do Vaccines Work Against the Omicron Variant?

The Omicron variant's spike protein has over 30 mutations, raising fears that it could evade vaccines and monoclonal antibody treatments. However, vaccines should retain some efficacy, and booster shots are necessary to strengthen antibody responses in vaccinated and previously infected individuals.

According to a recent preprint study, participants who had recently experienced COVID-19 had anti-spike proteins increase by almost 30 times after the second dose of their vaccination. After the booster, vaccinated patients who did not have COVID-19 exhibited a 25-fold increase in antibodies. The hope is that some of these antibodies will work against Omicron as well. Monoclonal antibody efficacy, on the other hand, may not fare well and suffer because they get only one type of antibody or two in the case of cocktails.

In this context, antiviral drugs will become critical if the Omicron variant evades immunity. Initial results show that Pfizer's protease inhibitor, paxlovid, has an efficacy of over 89% in preventing hospitalizations, with no deaths reported. Merck's new medicine, molnupiravir, has performed poorly, with a 30% decline in its efficacy in preventing hospitalizations. However, these drugs' effectiveness should not be influenced by the introduction of novel variants. The mechanism of action does not get based on the spike protein.

Battling the Omicron Variant: What Can People Do?

People must work together to avoid the healthcare system from becoming overburdened as a priority in dealing with COVID-19. If the Omicron variant's infectivity, mortality, and immune avoidance get verified, it will be critical that everyone who can get vaccinated, including those who have had previous COVID-19, do so.

Furthermore, pharmaceutical companies need time to develop, manufacture, and distribute antivirals and develop a new vaccine, if one is required. Travel bans will not stop the virus from spreading; rather, they will buy time for countermeasures to get put in place, which is necessary. Furthermore, careful adherence to public health measures, improved internal ventilation with periodic testing, and the use of N95 masks are critical.

N95 respirator masks, approved by the National Institute of Occupational Safety and Health (NIOSH), are still regarded as the gold standard of safety, followed by KN95 masks made by manufacturers on the CDC's whitelist. Surgical masks trail N95s and KN95s, and fabric masks trail even further, but cloth masks are a "better than nothing" choice at this stage.

Ultimately, the emergence of new variants emphasizes the importance of masks in the fight against the pandemic spread. While there are still questions about how effective vaccines and boosters will be against Omicron, the masks the world has been using throughout the pandemic have proven effective.

Masks are designed to block respiratory droplets and aerosols carrying viral particles, regardless of which virus is present in the particles. In other words, masks are effective against any disease conveyed by droplets or aerosols, and there is no evidence that Omicron gets spread any differently than previous viral variants.

In this regard, Merilogy provides rapid access to premium quality N95 particulate respirators that are NIOSH-approved.

Individuals must accept that this illness is here to stay and adapt their lifestyles in the long run. This adaptation includes increasing curbside and home delivery services and avoiding gatherings with strangers in places with inadequate ventilation.


The world should learn more about Omicron in the following days and weeks as results based on early studies undertaken by WHO and respectable universities and research groups unfold.

Government health organizations bear the greatest responsibility since they must increase their surveillance of positive COVID-19 cases by testing for the genetic signature to ensure that cases of Omicron get reported appropriately. This data, gathered through time, will aid everyone around the world in identifying the signs and severity of Omicron compared to other variants and establish guidelines for better combating its onslaught.

For the time being, the entire world must come together to keep each other safe. Stay at home as much as possible and wear your Merilogy N95 respirator mask.